Gabbroral 250mg Tablets contain Paromomycin (Aminosidine) Sulfate 250mg, an aminoglycoside antibiotic primarily used to treat certain intestinal protozoal infections such as amoebiasis, giardiasis, and cryptosporidiosis. It may also be prescribed in the management of hepatic encephalopathy and intestinal decontamination before certain surgical procedures.

Prescription Only Medicine (POM).

Key Benefits

• Helps treat intestinal amoebiasis
• Used in the management of giardiasis and cryptosporidiosis
• Acts locally within the gastrointestinal tract
• May be used as part of hepatic encephalopathy management
• Supports elimination of susceptible intestinal parasites
• Suitable for use under medical supervision

What It Is / How It Works

What is Gabbroral 250mg?

Gabbroral contains Paromomycin Sulfate, an aminoglycoside antibiotic that works mainly within the intestines. It is poorly absorbed into the bloodstream, allowing it to act directly on susceptible organisms in the gastrointestinal tract.

How It Works

Paromomycin interferes with protein synthesis in susceptible microorganisms, preventing their growth and survival. This helps clear intestinal infections caused by certain protozoa and parasites.

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Uses / Indications

Gabbroral 250mg Tablets may be prescribed for:

Intestinal Protozoal Infections

• Amoebiasis
• Giardiasis (Lambliasis)
• Cryptosporidiosis
• Balantidiasis

Other Medical Uses

• Adjunct treatment for hepatic encephalopathy
• Suppression of intestinal flora before certain bowel surgeries
• Selected parasitic intestinal infections as determined by a healthcare provider

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Dosage & Administration

Prescription Only Medicine

Use only as prescribed by a healthcare provider.

General Guidance

• Take the tablets exactly as prescribed.
• Usually taken with meals to reduce stomach discomfort.
• Complete the full prescribed course even if symptoms improve.
• Dosage depends on the condition being treated, body weight, and clinical assessment.

Do not self-medicate or alter the prescribed dose without professional advice.

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Possible Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Abdominal cramps
• Diarrhea
• Loss of appetite
• Stomach discomfort

Less common but serious side effects may include:

• Allergic reactions
• Kidney-related complications (particularly with prolonged use or intestinal lesions)
• Severe gastrointestinal symptoms

Seek medical attention if severe side effects occur.

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Warnings & Precautions

Do Not Use If:

• Allergic to paromomycin or other aminoglycoside antibiotics
• You have intestinal obstruction unless specifically directed by a healthcare provider

Consult Your Healthcare Provider Before Use If:

• You have kidney disease
• You have ulcerative intestinal conditions
• You are pregnant or breastfeeding
• You are taking other prescription medications

Important Safety Information

Gabbroral should be used cautiously in patients with ulcerative intestinal lesions because increased absorption may increase the risk of toxicity.

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Storage Instructions

• Store below 25°C.
• Keep in the original packaging.
• Protect from moisture and excessive heat.
• Keep out of reach of children.
• Do not use after the expiry date.

Mandatory Disclaimer

This medicine requires a valid prescription. Do not use without medical advice.

References

• DMRC Kenya – Gabbroral 250mg Tablets Information
• Official Gabbroral Product Information (Paromomycin 250mg)